PaB.BIOFABRICATION LAB
PUSAN NATIONAL UNIVERSITY
Pusan National University

3D Printing-assisted Biofabrication Lab.

Next-Generation
Bioartificial
Organs

  • 3D Printing
  • Biomaterials
  • Tissue Biomechanics
  • Mechanobiology

3D 프린팅과 생체재료 기술에
조직역학·기계생물학을 접목하여
기능성 인공조직과 바이오인공장기를 연구합니다.

Concept illustration of a three-head bioprinter behind an engineered skin patch and a vascular graft with softly differentiated tissue layers
Bioprinted tissue & scaffold concepts AI-generated illustration
PaB LAB / YANGSAN CAMPUSSCROLL TO EXPLORE ↓
RECRUITMENT2027 전기 대학원생 · 연구원 모집View opportunities ↗
01 / What We Do

3D Printing-assisted
Biofabrication Lab.

부산대학교 3D 바이오가공기술 연구실

Our laboratory develops next-generation bioartificial organs by integrating 3D printing, biomaterials, biomechanics, bioelectronics and artificial intelligence.

At the core of our research is 3D Printing-assisted Biofabrication & Biomanufacturing. We use micro- and nano-scale printing technologies to engineer functional tissues, implantable regenerative constructs, mini-organs and organ-on-a-chip platforms.

The Lab at a Glance

We integrate biofabrication, biomechanics, medical devices, and AI to engineer
next-generation platforms for healthcare and regenerative medicine.

01MAKE

Biofabrication &Biomanufacturing

Micro/Nano 3D PrintingBiomaterials / Bioinks

핵심 연구
  • 마이크로·나노 3D 프린팅
  • 바이오잉크 · 생체재료
대표 응용
  • 이식형 재생조직
  • 미니장기
  • Organ-on-a-Chip
02MATURE

Biomechanics &Mechanobiology

Mechanical & ElectricalStimulation · Bioreactor

핵심 연구
  • 물리적 자극(전단·인장·압축·전기)
  • 바이오리액터 시스템
대표 응용
  • 조직 성숙화
  • 질환 모델링
  • 대량 세포배양
03TREAT

PrintedMedical Devices

Microneedle · BioelectronicsBiosensor

핵심 연구
  • 마이크로니들 · 바이오일렉트로닉스
  • 바이오센서
대표 응용
  • 약물전달
  • 조직 자극
  • 생체신호 측정
04DESIGN

AI-assistedInverse Design

AI · OptimizationVascular Network Design

핵심 연구
  • AI 기반 구조·물성 역설계
  • 혈관 네트워크 설계
대표 응용
  • 혈관 네트워크
  • 맞춤형 조직공학 구조체

We investigate how mechanical and electrical microenvironments regulate cell and tissue behavior. By recreating physiologically relevant shear, stretch, compression and electrical stimulation, we develop bioreactor systems for tissue maturation, disease modeling and large-scale cell and tissue culture.

Beyond tissue fabrication, we translate printing technologies into medical devices, including microneedles for drug delivery, printed bioelectronics for tissue stimulation and biosensors for monitoring biological signals.

We are also expanding toward AI-assisted inverse design to determine tissue architectures and material properties from desired biological functions, with interests in vascular network design and tissue-specific mechanical property optimization.

03 / Publications

Selected Publications

All publications ↗
2026
BIOFABRICATION

Artificial intelligence in 3D bioprinting and biofabrication: a validation-stringency assessment

Jae-Seong Lee, Joo-Hee Cha, Byoung Soo Kim

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2026
ADVANCED SCIENCE

Mechanical Stimuli-Induced Manipulation of Malignant Behavior in Bioprinted, Cancer Microtissues via PI3K/NF-κB Activation

Seok-Hyeon Lee et al.

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2025
ADVANCED FUNCTIONAL MATERIALS

Embedded 3D-Coaxial Bioprinting of Stenotic Brain Vessels with a Mechanically Enhanced Extracellular Matrix Bioink for Investigating Hemodynamic Force-Induced Endothelial Responses

Wonbin Park, Min-Ju Choi, Jae-Seong Lee et al.

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04 / Lab Life

Lab Life

All activities ↗
Seminar

Seminar with Professor Yanghee Kim

사우스햄튼대학교 김양희 교수님이 연구실을 방문해 세미나를 진행했습니다. 한국–영국 교류사업을 통해 공동연구 교류를 이어가고 있습니다.

Pusan National University

Conference & Exchange

Southampton Lab Visit & TCES 2026

이석현·이정호 학생이 사우스햄튼대학교 연구실을 방문하고, 영국 브라이턴에서 열린 TCES 2026에서 구두·포스터 발표를 진행했습니다. 두 학생 모두 수고하셨습니다.

Southampton & Brighton, UK

Conference

KTERMS 2026 Conference

이석현·이정호 학생이 서울아산병원에서 열린 제26차 한국조직공학·재생의학회 학술대회에 참석해 연구 결과를 발표했습니다. 두 학생 모두 수고하셨습니다.

Asan Medical Center, Seoul

05 / Join the lab

Graduate & Research Opportunities

2027 전기 대학원생·연구원 모집 · Undergraduate internships

Application & Contact ↗